FP6 priority |
1.1.1 Genomics and Biotechnology for Health |
Title of the proposal |
Neurogenesis and ependymal cells transformation regularities in newborn, adult and aged rodents in health and pathology |
Institute |
Slovak Academy of Sciences, Institute of Neurobiology
Soltesovej 4, 040 01 Kosice, Slovak Republic
www.saske.sk/inb |
Contact |
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Research subject for a potential FP6 project
The rostral migratory stream, functionally spanning the subventricular zone and olfactory bulb, permits comparison of cellular mechanisms involved in the immature and adult neurogenesis cascade and offers a unique opportunity to study proliferation, migration, and integration of new neurons into functional circuits throughout the live. Our laboratory, focused on neuromorphological and behavioral research, performs olfactory bulbectomy (in neonatal as well as adult rats) as a simple model of neurogenic regions injury. |
Recent international cooperation of the research team
Department of Comparative Physiology, University of Szeged, Kozepfasor 52, H-6726 Szeged, Hungary |
Proposerīs relevant publications related to the research subject
AMEMORI, T., ERMAKOVA, I.V., BURESOVA, O., ZIGOVA, T., RACEKOVA, E., BURES, J.: Brain transplants enhance rather than reduce the impairment of spatial memory and olfaction in bulbectomized rats. Behav. Neurosci., 103, 1989, p. 61-70.
RACEKOVA, E., VANICKY, I., ZIGOVA T.: Correlation of functional alteration with lesion extent after olfactory bulbectomy in rats. Intern. J. Neuroscience, 79, 1994, p. 13-20.
RACEKOVA, E., RACEK, L., ORENDACOVA, J.: Olfactory bulbectomy of neonatal rats influences proliferation of subventricular zone neuronal precursors. Chem. Listy 94, 2000, p. 749-750. |
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